Drug Delivery Model
In this work, MATLAB is used to simulate the delivery of novel
nanoparticle chemotherapy drug to cancerous tissue. Simulation allows
scientists to predict experimental outcomes and thus reduce the cost of
development and time to clinical relevance. The movies below show the
initial proliferation of a cluster of tumor cells before death once the
drug is administered. The simulation model includes blood vessels, tumor
cells, and healthy cells and an engine to calculate the spatial
distributions of both drug and oxygen. Jacket is used to speed up the
diffusion calculations for the drug and oxygen within the tissue.
Authors: MIBLAB at the
Georgia Institute of
Technology. Center
for Cancer Nanotechnology Excellence at Georgia Tech and Emory
Speedup: 70X
System Specs: MATLAB R2008A, an NVIDIA Tesla C870 GPU, and an Intel E2180 CPU
Drug Delivery Videos
Simulation of Cancer Cell Response to Drug Delivery.
Diffusion Profile of Drug Delivery.
Tissue Oxygenation Profile.
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